Feedback control of neuromuscular blockade.

Neuromuscular blockade in children.

Neuromuscular blocking agents (NMBAs) have been widely used to control patients who need to be immobilized for some kind of medical intervention, such as an invasive procedure or synchronism with mechanical ventilation. The purpose of this monograph is to review the pharmacology of the NMBAs, to compare the main differences between the neuromuscular junction in neonates, infants, toddlers and a...

Monitoring neuromuscular blockade.

Neuromuscular-blocking agents (NMBA) have been used in clinical anesthesia for nearly 60 years. In the perioperative period, a variety of factors can influence a patient’s response to these drugs. To precisely titrate NMBAs to clinical effects in the anesthetized patient, the application of neuromuscular monitoring is essential. The use of a peripheral nerve stimulator allows the clinician to a...

A compartmental model-based control strategy for NeuroMuscular Blockade level. ⋆

This paper presents a compartmental model-based control strategy to drive the NeuroMuscular Blockade level of patients undergoing general anesthesia to a predefined target. For that purpose, a compartmental realization of a minimally parameterized nonlinear Wiener model was derived and used on an adapted version of the standard compartmental control law for linear systems. The identification of...

An Improved Strategy for NeuroMuscular Blockade Control with Parameter Uncertainty

Neuromuscular blockade in the ICU.

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